The cyber security learning and research environment

This report outlines the design and configuration of the Cyber Security Learning and Research Environment (CLARE). It explains how such a system can be implemented with minimal hardware either on a single machine or across multiple machines. Moreover, details of the design of the components that constitute the environment are provided alongside sufficient implementation and configuration documentation to allow for replication of the environment

Managing customer relationships: Should managers really focus on the long term?

Researchers and business thought leaders have emphasized that, towards maximizing the lifetime value of customers, firms must manage customer relationships for the long term. In contrast to this recommendation, we demonstrate that firm profits in competitive environments are maximized when managers focus on the short term with respect to their customers. Intuitively, while a long term focus yields more loyal customers, it sharpens short term competition to gain and keep customers to such an extent that overall firm profits are lower than when managers focus on the short term. Further, a short term focus continues to deliver higher profits even when customer loyalty yields a higher share-of-wallet or reduced costs of service from the perspective of the firm. Intuitively, while such revenue enhancement or cost reduction effects enhance the proverbial pot of gold at the end of the rainbow, they lead to even more intense competition to gain and keep customers in the short term. These findings suggest that the competitive implications of a switch to a long term customer focus must be carefully examined before such a switch is advocated or implemented. Paradoxically, customer lifetime value may be maximized when managers focus on the short term.target pricing; customer equity; price discrimination; customer relationship marketing; customer acquisition; customer retention;

The SpinBus Architecture: Scaling Spin Qubits with Electron Shuttling

Quantum processor architectures must enable scaling to large qubit numbers while providing two-dimensional qubit connectivity and exquisite operation fidelities. For microwave-controlled semiconductor spin qubits, dense arrays have made considerable progress, but are still limited in size by wiring fan-out and exhibit significant crosstalk between qubits. To overcome these limitations, we introduce the SpinBus architecture, which uses electron shuttling to connect qubits and features low operating frequencies and enhanced qubit coherence. Device simulations for all relevant operations in the Si/SiGe platform validate the feasibility with established semiconductor patterning technology and operation fidelities exceeding 99.9 %. Control using room temperature instruments can plausibly support at least 144 qubits, but much larger numbers are conceivable with cryogenic control circuits. Building on the theoretical feasibility of high-fidelity spin-coherent electron shuttling as key enabling factor, the SpinBus architecture may be the basis for a spin-based quantum processor that meets the scalability requirements for practical quantum computing.Comment: 15 pages, 9 figure

CD8 Epitope Escape and Reversion in Acute HCV Infection

In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8+ cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. Despite these responses, 70–80% of individuals develop persistent infection. Although viral escape from CD8 responses has been illustrated in the chimpanzee model of HCV infection, the effect of CD8 selection pressure on viral evolution and containment in acute HCV infection in humans remains unclear. Here, we examined viral evolution in an immunodominant human histocompatibility leukocyte antigen (HLA)-B8–restricted NS3 epitope in subjects with acute HCV infection. Development of mutations within the epitope coincided with loss of strong ex vivo tetramer and interferon γ enzyme-linked immunospot responses, and endogenous expression of variant NS3 sequences suggested that the selected mutations altered processing and presentation of the variant epitope. Analysis of NS3 sequences from 30 additional chronic HCV-infected subjects revealed a strong association between sequence variation within this region and expression of HLA-B8, supporting reproducible allele-specific selection pressures at the population level. Interestingly, transmission of an HLA-B8–associated escape mutation to an HLA-B8 negative subject resulted in rapid reversion of the mutation. Together, these data indicate that viral escape from CD8+ T cell responses occurs during human HCV infection and that acute immune selection pressure is of sufficient magnitude to influence HCV evolution

The Baryon Oscillation Spectroscopic Survey of SDSS-III

The Baryon Oscillation Spectroscopic Survey (BOSS) is designed to measure the scale of baryon acoustic oscillations (BAO) in the clustering of matter over a larger volume than the combined efforts of all previous spectroscopic surveys of large scale structure. BOSS uses 1.5 million luminous galaxies as faint as i=19.9 over 10,000 square degrees to measure BAO to redshifts z<0.7. Observations of neutral hydrogen in the Lyman alpha forest in more than 150,000 quasar spectra (g<22) will constrain BAO over the redshift range 2.15<z<3.5. Early results from BOSS include the first detection of the large-scale three-dimensional clustering of the Lyman alpha forest and a strong detection from the Data Release 9 data set of the BAO in the clustering of massive galaxies at an effective redshift z = 0.57. We project that BOSS will yield measurements of the angular diameter distance D_A to an accuracy of 1.0% at redshifts z=0.3 and z=0.57 and measurements of H(z) to 1.8% and 1.7% at the same redshifts. Forecasts for Lyman alpha forest constraints predict a measurement of an overall dilation factor that scales the highly degenerate D_A(z) and H^{-1}(z) parameters to an accuracy of 1.9% at z~2.5 when the survey is complete. Here, we provide an overview of the selection of spectroscopic targets, planning of observations, and analysis of data and data quality of BOSS.Comment: 49 pages, 16 figures, accepted by A

The Ninth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the SDSS-III Baryon Oscillation Spectroscopic Survey

The Sloan Digital Sky Survey III (SDSS-III) presents the first spectroscopic data from the Baryon Oscillation Spectroscopic Survey (BOSS). This ninth data release (DR9) of the SDSS project includes 535,995 new galaxy spectra (median z=0.52), 102,100 new quasar spectra (median z=2.32), and 90,897 new stellar spectra, along with the data presented in previous data releases. These spectra were obtained with the new BOSS spectrograph and were taken between 2009 December and 2011 July. In addition, the stellar parameters pipeline, which determines radial velocities, surface temperatures, surface gravities, and metallicities of stars, has been updated and refined with improvements in temperature estimates for stars with T_eff<5000 K and in metallicity estimates for stars with [Fe/H]>-0.5. DR9 includes new stellar parameters for all stars presented in DR8, including stars from SDSS-I and II, as well as those observed as part of the SDSS-III Sloan Extension for Galactic Understanding and Exploration-2 (SEGUE-2). The astrometry error introduced in the DR8 imaging catalogs has been corrected in the DR9 data products. The next data release for SDSS-III will be in Summer 2013, which will present the first data from the Apache Point Observatory Galactic Evolution Experiment (APOGEE) along with another year of data from BOSS, followed by the final SDSS-III data release in December 2014.Comment: 9 figures; 2 tables. Submitted to ApJS. DR9 is available at http://www.sdss3.org/dr

The Eleventh and Twelfth data releases of the Sloan Digital Sky Survey: Final data from SDSS-III

The third generation of the Sloan Digital Sky Survey (SDSS-III) tookdata from 2008 to 2014 using the original SDSS wide-field imager, theoriginal and an upgraded multi-object fiber-fed optical spectrograph, anew near-infrared high-resolution spectrograph, and a novel opticalinterferometer. All of the data from SDSS-III are now made public. Inparticular, this paper describes Data Release 11 (DR11) including alldata acquired through 2013 July, and Data Release 12 (DR12) adding dataacquired through 2014 July (including all data included in previous datareleases), marking the end of SDSS-III observing. Relative to ourprevious public release (DR10), DR12 adds one million new spectra ofgalaxies and quasars from the Baryon Oscillation Spectroscopic Survey(BOSS) over an additional 3000 deg2 of sky, more than triplesthe number of H-band spectra of stars as part of the Apache PointObservatory (APO) Galactic Evolution Experiment (APOGEE), and includesrepeated accurate radial velocity measurements of 5500 stars from theMulti-object APO Radial Velocity Exoplanet Large-area Survey (MARVELS).The APOGEE outputs now include the measured abundances of 15 differentelements for each star. In total, SDSS-III added 5200 deg2 ofugriz imaging; 155,520 spectra of 138,099 stars as part of the SloanExploration of Galactic Understanding and Evolution 2 (SEGUE-2) survey;2,497,484 BOSS spectra of 1,372,737 galaxies, 294,512 quasars, and247,216 stars over 9376 deg2; 618,080 APOGEE spectra of156,593 stars; and 197,040 MARVELS spectra of 5513 stars. Since itsfirst light in 1998, SDSS has imaged over 1/3 of the Celestial sphere infive bands and obtained over five million astronomical spectra.Fil: Alam, Shadab. University of Carnegie Mellon; Estados UnidosFil: Albareti, Franco D.. Universidad Autónoma de Madrid; EspañaFil: Prieto, Carlos Allende. Universidad de La Laguna; EspañaFil: Anders, F.. Leibniz Institute For Astrophysics Potsdam; AlemaniaFil: Anderson, Scott F.. University of Utah; Estados UnidosFil: Anderton, Timothy. University of Utah; Estados UnidosFil: Andrews, Brett H.. Ohio State University; Estados Unidos. University of Pittsburgh; Estados UnidosFil: Armengaud, Eric. Service de Physique Des Particules; FranciaFil: Aubourg, Éric. Université Paris Diderot - Paris 7; FranciaFil: Bailey, Stephen. Lawrence Berkeley National Laboratory; Estados UnidosFil: Basu, Sarbani. University of Yale; Estados UnidosFil: Bautista, Julian E.. Université Paris Diderot - Paris 7; FranciaFil: Beaton, Rachael L.. University of Virginia; Estados UnidosFil: Beers, Timothy C.. University of Notre Dame; Estados UnidosFil: Bender, Chad F.. Pennsylvania State University; Estados UnidosFil: Berlind, Andreas A.. Vanderbilt University; Estados UnidosFil: Beutler, Florian. Lawrence Berkeley National Laboratory; Estados UnidosFil: Bhardwaj, Vaishali. Lawrence Berkeley National Laboratory; Estados UnidosFil: Bird, Jonathan C.. Vanderbilt University; Estados UnidosFil: Bizyaev, Dmitry. Apache Point Observatory; Estados UnidosFil: Blake, Cullen H.. University of Pennsylvania; Estados UnidosFil: Blanton, Michael R.. New York University; Estados UnidosFil: Blomqvist, Michael. University of California at Irvine; Estados UnidosFil: Bochanski, John J.. University of Washington; Estados UnidosFil: Bolton, Adam S.. University of Utah; Estados UnidosFil: Bovy, Jo. Institute For Advanced Studies; Estados UnidosFil: Shelden, Bradley, A.. Apache Point Observatory; Estados UnidosFil: Brandt, W. N.. Pennsylvania State University; Estados UnidosFil: Brauer, D. E.. Leibniz Institute For Astrophysics Potsdam; AlemaniaFil: Nuza, Sebastian Ernesto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; Argentina. Institut Max Planck Fuer Gesellschaft. Max Planck Institute For Extraterrestrial Physics; AlemaniaFil: Scoccola, Claudia Graciela. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas; Argentin

Cosmological implications of baryon acoustic oscillation measurements

We derive constraints on cosmological parameters and tests of dark energy models from the combination of baryon acoustic oscillation (BAO) measurements with cosmic microwave background (CMB) data and a recent reanalysis of Type Ia supernova (SN) data. In particular, we take advantage of high-precision BAO measurements from galaxy clustering and the Lyman-α forest (LyaF) in the SDSS-III Baryon Oscillation Spectroscopic Survey (BOSS). Treating the BAO scale as an uncalibrated standard ruler, BAO data alone yield a high confidence detection of dark energy; in combination with the CMB angular acoustic scale they further imply a nearly flat universe. Adding the CMB-calibrated physical scale of the sound horizon, the combination of BAO and SN data into an “inverse distance ladder” yields a measurement of H0 =67.3 ± 1.1 km s-1 Mpc-1, with 1.7% precision. This measurement assumes standard prerecombination physics but is insensitive to assumptions about dark energy or space curvature, so agreement with CMB-based estimates that assume a flat Λ CDM cosmology is an important corroboration of this minimal cosmological model. For constant dark energy (Λ), our BAO + SN + CMB combination yields matter density Ωm = 0.301 ± 0.008 and curvature Ωk = -0.003 ± 0.003. When we allow more general forms of evolving dark energy, the BAO + SN + CMB parameter constraints are always consistent with flat Λ CDM values at ≈1σ. While the overall χ2 of model fits is satisfactory, the LyaF BAO measurements are in moderate (2–2.5σ) tension with model predictions. Models with early dark energy that tracks the dominant energy component at high redshift remain consistent with our expansion history constraints, and they yield a higher H0 and lower matter clustering amplitude, improving agreement with some low redshift observations. Expansion history alone yields an upper limit on the summed mass of neutrino species, ∑mν (95% confidence), improving to ∑mν if we include the lensing signal in the Planck CMB power spectrum. In a flat Λ CDM model that allows extra relativistic species, our data combination yields Neff = 3.43 ± 0.26; while the LyaF BAO data prefer higher Neff when excluding galaxy BAO, the galaxy BAO alone favor Neff ≈ 3. When structure growth is extrapolated forward from the CMB to low redshift, standard dark energy models constrained by our data predict a level of matter clustering that is high compared to most, but not all, observational estimates